Uniting Large Pharma, Innovative Biotech and Leading Academics to Eliminate the Boundaries of Druggability with Novel Covalent Drugs
With continued advancements in screening platforms and proteomics, the covalency renaissance continues as biopharma race to unlock hard-to-target proteins across oncology, immunology and CNS. We are witnessing this industry make great strides in utilizing novel covalent modalities and elucidating novel warheads to target amino acids beyond cysteine. However, developing covalent drugs remains no easy feat, as knowledge gaps persist in balancing reactivity and selectivity, de-risking the ligandability of alternative residues, and tackling PKPD disconnects and efficiency bottlenecks to successfully develop potent covalent drugs for unmet clinical need.
The 2nd Covalent Drug Discovery and Development Summit returns as the central hub dedicated to every aspect of covalency from discovery to translation and clinical development, equipping 100+ global covalency leaders with the means to expand the druggable proteome.
With continued advancements in screening platforms and proteomics, the covalency renaissance continues as biopharma race to unlock hard-to-target proteins across oncology, immunology and CNS. We are witnessing this industry make great strides in utilizing novel covalent modalities and elucidating novel warheads to target amino acids beyond cysteine. However, developing covalent drugs remains no easy feat, as knowledge gaps persist in balancing reactivity and selectivity, de-risking the ligandability of alternative residues, and tackling PKPD disconnects and efficiency bottlenecks to successfully develop potent covalent drugs for unmet clinical need.
The 2nd Covalent Drug Discovery and Development Summit returns as the central hub dedicated to every aspect of covalency from discovery to translation and clinical development, equipping 100+ global covalency leaders with the means to expand the druggable proteome.
