Dr Katherine Wheelhouse FÂ鶹AV
Winner: 2022 Organic Division mid-career Award: MSD Award
GlaxoSmithKline
For contributions to the application and industrialisation of chemical catalysis in the pharmaceutical industry in the pursuit of more sustainable synthesis of medicines.
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By collaborating, we can bring in more diverse viewpoints, which is where true innovation arises.
Katherine is a chemist within Drug Substance Development, a multi-functional department at GlaxoSmithKline (GSK) that includes chemistry, chemical engineering and materials science groups working collaboratively to develop small molecule drugs.
The department’s accountabilities include determining the best way to construct potential drug molecules, both in terms of the route, i.e., the sequence of chemical intermediates and the process, which is essentially the recipe for each step. This work enables successful scale-up of drug candidates from milligram to multi-kilogram and even tonne scale, and the eventual transfer to manufacturing plants to produce the high-quality active ingredient required for formulation into the final medicine prescribed to the patient.
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